The recent Steven Soderbergh (Ocean’s Eleven, Traffic) thriller Side Effects is making its way to home video with the announcement that the movie will be arriving on Blu-ray and DVD on May 21st. If you can’t wait until then, it will also be available via digital download beginning on May 7th.

The movie stars Rooney Mara (The Girl With the Dragon Tattoo, The Social Network) as a woman who begins suffering from terrifying anxiety after her husband (Channing Tatum — Magic Mike, 21 Jump Street) is released from prison for insider trading. Seeking an answer, she sees psychiatrist Dr. Banks (Jude Law — Sherlock Holmes, Road to Perdition), who prescribes her an experimental new drug, which ends up having deadly side effects.

Side Effects
Directed by Steven Soderbergh
Written by Scott Z. Burns
Starring: Rooney Mara, Channing Tatum, Jude Law, Catherine Zeta-Jones
Open Road Films
Rated R | 106 Minutes
Release Date: February 8th, 2013

Directed by Steven Soderbergh (Magic Mike) and written by Scott Z. Burns (Contagion), Side Effects begins as an exploration of the pharmaceutical industry and experimental mood-altering drugs. But slowly, Soderbergh’s film becomes something different altogether.

The film follows Emily (Rooney Mara) and her husband Martin (Channing Tatum), a New York couple whose world unravels when a new drug prescribed by Emily’s psychiatrist (Jude Law) – intended to treat anxiety and depression – has unexpected side effects.

Accustomed to a life of luxury and blissful matrimony, Emily’s world collapsed when her dream husband was arrested for insider trading. Since then, she has been struggling with depression and anxiety about the future, or her lack of one. After serving a 4-year prison term, Martin has returned home to help rebuild his life with Emily.

Emily begins seeing Dr. Jonathan Banks (Law), who recommends better living through chemistry via a new SSRI (selective serotonin reuptake inhibitor), Ablixa. In the past, Emily hasn’t had much luck with drugs like Prozac, Welbutrin, Zoloft, or Effexor, so she’s willing to try the pharmaceutical industry’s latest ‘miracle cure.’

The cast of Steven Soderbergh‘s upcoming drama, Side Effects, is coming together, and now a new star has been brought in to replace the departed Blake Lively.

It’s being reported that Rooney Mara, star of David Fincher’s The Social Network and The Girl With The Dragon Tattoo, will replace Lively on the film, which will see her playing a highly depressed and overly medicated woman who’s anxious about her soon-to-be-released husband from prison.

Despite losing Annapurna Films as a co-financer just a week after getting them on board, the new Steven Soderbergh film Side Effects just got a whole lot classier.

Deadline is reporting that Catherine Zeta-Jones has joined the film’s cast, which includes Blake Lively, Jude Law, and Channing Tatum.

Penned by Scott Z. Burns, the film follows a woman (Lively) who’s dealing with much anxiety and depression, particularly over the upcoming release of her husband (played by Tatum) from prison, leading her to take dangerous amounts of prescription drugs and into a relationship with a doctor (Law). Zeta-Jones plays Dr. Erica Siebert.