The female lead has been cast for Dumb and Dumber To, the sequel to the 1994 Peter Farrelly and Bobby Farrelly comedy hit Dumb and Dumber.

It’s been reported that Laurie Holden has been chosen for the role of Adele Pichlow, an up-to-no-good wife of a doctor who plans to use Lloyd Christmas (Jim Carrey) and Harry Dunne (Jeff Daniels) to cover up her tracks.

We found out back in 2011 that the Peter Farrelly and Bobby Farrelly were planning a sequel to their hit 1994 comedy Dumb and Dumber with original stars Jim Carrey and Jeff Daniels, which was later confirmed by the Farrellys. Since then the project has had ups and downs, from Carrey departing the project to Daniels saying it would begin production this summer to Warner Brothers deciding they would not be greenlighting the sequel.

With all of that now in the past, the Farrelly brothers look to the future. After WB decided they didn’t want to make the movie, it was time to begin shopping it around to other studios who might be interested, and at least one of them was just that. Taking to the Twitter, the Farrellys have announced that the sequel, officially titled Dumb and Dumber To, will go into production with Universal Pictures and Red Granite Pictures.

Peter and Bobby Farrelly‘s Dumb and Dumber To nearly fell apart after Jim Carrey reportedly walked out after he felt that Warner Brothers was less than enthusiastic about the seuqel. A few months after, Jeff Daniels quelled some fears saying that Carrey wants to be back, and that production for the long-gestating sequel would begin soon. But that’s history.

The Hollywood Reporter has word now that the studio is dropping the project from its distribution slate, which means that competing distributors are now able to buy the rights for the film.

It’s hard to describe a movie like Movie 43, because there is no actual place to start. The comedy is a collection of shorts and skits directed by – take a deep breath now – Patrick Forsberg, Peter Farrelly, Elizabeth Banks, Steven Brill, Steve Carr, Tusty Cundieff, James Duffy, Griffin Dunne, James Gunn, Bob Odenkirk, and Brett Ratner. If you thought the directors list was big, just wait until you see the cast list.

This hilarious red band trailer features comedic acts that can only be described as vulgar, disgusting, provocative, offensive, and other repulsive adjectives you can think of. But it’s all for the sake of comedy, and this red band trailer reveals that Movie 43 has the potential to be a daring comedy. Check out the trailer and the actors involved below.

The film stars so many people, that it’s impossible to fit them in this opening text. Take a deeper breath than the one you took before, as this is the cast of Movie 43…

At a press junket for their latest movie The Three Stooges, directors Peter and Bobby Farrelly took some time to discuss the long-rumored sequel to their 1994 smash hit debut Dumb & Dumber, which also helped launch the career of star Jim Carrey. Coming Soon reports that Peter Farrelly said that the movie is definitely in the works with the stars returning and that the brothers are looking to begin production later this year on Dumb & Dumber 2 (title subject to change).”